Here is a great article that talks about how to manage working remotely. Even though it refers to being a freelancer or contractor, the tips are equally important for employees working from home or remotely on a regular basis. Even applies if you have an office and a desk there if you do lots of work at home rather than in the office.
As we get more and more mobile due to technology we need to create work spaces at home that enable us to distinguish between work and family (which I am currently not doing well as I type this blog post on the lounge in front of the TV!)